Women's Fertility Test - EverlyWell vs LetsGetChecked and ZRT Lab Review

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The topic of hormone balance and imbalance can be confusing and overwhelming. Just trying to understand how the perfect harmonious balance in hormones affects fertility is a challenge, let alone choosing a testing company to provide you with answers.   With so many home based testing methods on the market today, how to know which is best to suit your unique needs can be a challenge.

We’ve reviewed three of the leading online direct to consumer at home health lab companies offering at-home fertility tests. 

Best At Home Women's Fertility Hormone Tests

 LetsGetChecked

LetsGetChecked

 EverlyWell

EverlyWell

 ZRT Laboratory

ZRT Laboratory


Research Table of Contents

• Why Fertility Testing
• Menstrual Cycle Mysteries
• EverlyWell Women's Fertility Test Review
• LetsGetChecked Female Hormone Test Review
• ZRT Laboratory Fertility Profile Test Review

Researcher:  Lori Smith

Date:  May 1, 2018

 

Why fertility testing?

Home based fertility testing may be a viable option for women seeking answers into their hormonal health. It is ideal for women who may be experiencing menstrual abnormalities or irregularity, difficulty conceiving or those who are wanting to better understand their hormones prior to conceiving. 

For a woman’s reproductive system to function normally, there needs to be a harmonious balance of several hormones, some of which include:

  • Estrogen

  • Follicle stimulating hormone (FSH)

  • Lutenizing hormone (LH)

  • Prolactin

  • Testosterone

  • Thyroid stimulating hormone (TSH)


Within this article, we will briefly discuss some of the hormones needed for normal reproductive function. For a more detailed discussion on hormonal health, check out our article Home Based Hormone Testing for Women (and MEN).

Fertility Hormones: Mystery Solved

Every woman’s menstrual cycle is different in cycle length, bleeding time and bleeding amount but there are some commonalities that many women experience. Typically speaking, a menstrual cycle can range anywhere from 25-36 days, however, there are many women who report menstrual cycle irregularities for a variety of reasons. For most women menstrual bleeding ranges from 3-7 days with an estimated blood loss of ½ to 2 ½ ounces, however, as with menstrual cycle ranges, blood flow rage and clotting vary person to person. 

Hormonal balance is vital in regulation of the menstrual cycle and preparing the body to conceive during the three phases of the menstrual cycle. 

The Follicular Phase

The follicular phase begins on day one of a woman’s period which is defined as the first day of bleeding and lasts 13-14 days thereafter. This is the time when the lining of the uterus is shed due to low levels of estrogen and progesterone and no implanted embryo. During this phase, the body prepares for ovulation by developing many ovarian follicles, however, typically only one follicle will mature to be released during ovulation. 

This phase is regulated by the hormone follicle-stimulating hormone or FSH produced by the pituitary gland, which will eventually naturally decrease to a lower level during this phase so only one follicle fully develops and produces the hormone estrogen. The estrogen released by this dominant follicle is now preparing the uterine lining to begin to thicken again and help with the surge in the luteinizing hormone needed for ovulation to occur. 

The Ovulatory Phase

The ovulatory phase is when the body prepares for ovulation (release of the egg) for fertilization. During this phase, the hormones luteinizing hormone (LH) and FSH surge, triggering the body to release an egg within the following 16-32 hours- the length of the ovulatory phase.

Although the ovulatory phase can last for upwards of 32 hours, an egg is only viable and able to be fertilized within the short, 12 hour window following expulsion from the ovarian follicle. 

The Luteal Phase

Since ovulation has already occurred, hormone dominance changes. During the luteal phase which lasts approximately 14 days, LH and FSH are low and estrogen and progesterone levels rise. 

Following ovulation, the hole that was created to expel the egg closes and forms the progesterone producing corpus luteum. Progesterone will nourish an early pregnancy and both estrogen and progesterone thicken the uterine lining to prepare for implantation if fertilization occurs and dilate the milk ducts leading to breast tenderness and swelling. During this phase, elevated levels of progesterone also cause thickening of cervical mucous to prevent infection and a temperature rise.

Should either conception or implantation not occur, hormone levels will change once again with estrogen and progesterone levels decreasing to signal the body to start a new menstrual cycle. 

Note: Changes in other hormones including thyroid stimulating hormone and prolactin, can also play a role in fertility and may also need testing.

Hormone Takeaway and Conditions Affecting Hormone Levels

As you can see, optimal hormone balance is vital in regulation of menstruation and conception. Conditions like polycystic ovarian syndrome (PCOS), thyroid disease, progesterone resistance, diabetes, certain ovarian or adrenal gland tumors and others can lead to menstrual abnormalities and contribute to infertility. There are also lifestyle choices that may contribute to hormone imbalance such as strenuous exercise which can alter hormone levels. 

Hormone testing will allow your healthcare provider to put the pieces of the puzzle together to determine which hormones are imbalanced and provide insight into what may be causing this to occur. Additional testing can then be recommended to evaluate for, in some cases, treatable conditions to regulate hormones. 


Everly Well Women's Fertility Test Review

Price:  $159.00

Collection:  Blood, finger stick collection

Markers Measured:  Estradiol, Luteinizing Hormone, Follicle‑Stimulating Hormone (FHS) , Total Testosterone, Thyroid‑Stimulating Hormone (TSH).

Restrictions:  Tests cannot be shipped to New York, New Jersey, Maryland and Rhode Island

The EverlyWell Women’s Fertility Test is an ideal home-based hormone testing method for women wanting to evaluate their hormone levels prior to conceiving and to evaluate their menstrual health. 

  • Instructional videos

  • Itemized receipt for HSA/FSA reimbursements avaialble upon request and accept HAS/FSA payment

  • Online chat Monday-Friday from 9 am to 5 pm CST hours and very responsive

  • Email support available Sunday-Friday

  • Phone support Monday-Friday from 9 am to 5 pm CST

  • Accepts FSA/HSA payments and major CC payments

  • Results reviewed by physician- no follow up available. Recommended to present results to patients own healthcare provider.

  • Easy testing method with video instruction, great customer service, quick results turn around, Accept HSA/FSA payments

  • Test does not cover other hormones like Prolactin and hormones specific to ovarian reserve. These tests require the purchase of additional tests.

  • Testing only available certain US states and not abroad.

  • No app.

PROS

Easy testing method with video instruction, great customer service, quick results turn around, Accept HSA/FSA payments

CONS

·   Test does not cover other hormones like Prolactin and hormones specific to ovarian reserve. These tests require the purchase of additional tests. 

·  Testing only available certain US states and not abroad.

BOTTOM LINE

The EverlyWell Women’s Fertility Test is an ideal home-based hormone testing method for women wanting to evaluate their hormone levels prior to conceiving and to evaluate their menstrual health. 


LetsGetChecked Female Hormone Review

Price:  $129.00

Collection:  Blood, finger stick collection

Markers Measured:  Follicle Stimulating Hormone (FSH), Lutenising Hormone (LH), Prolactin Oestradiol.

Restrictions:  Tests cannot be shipped to New York, New Jersey, Maryland and Rhode Island

The Female Hormone test must be taken on Day 3 of your menstrual cycle. Day 3 is the third day of your period (blood flow, not spotting before 5pm is Day 1).

  • App to activate kit

  • Online chat which is very responsive

  • Email support

  • Phonesupport

  • Instructional videos

  • Major payment methods accepted including PayPal, Visa, MC, Discover, American Express, Diners Club and JCB

PROS

Easy testing method with video instruction, great customer service, quick results turn around and test result support.

CONS

This test does not cover other hormones like Total Testosterone, Thyroid Stimulating Hormone, progesterone or hormones to test specifically for ovarian reserve. These require the purchase of additional tests.

BOTTOM LINE

The LetsGetChecked Female Hormone test is ideal for those who are wanting to get a broad spectrum look into their hormonal health to see if there are any abnormalities which could be affecting fertility. These may include women who are currently trying to conceive, planning for future conception or wanting to evaluate their potential risk of polycystic ovarian syndrome (PCOS).


ZRT Fertility Profile

Price:  $165.00

Collection Method:  Blood & Saliva

Markers Measured:  Estradiol, Progesterone, Testosterone, Sex Hormone Binding Globulin (SHBG), DHEA-STSH, Free Triiodothyronine (fT3), Free Thyroxine, (fT4), Thyroid peroxidase (TPO), Follicle‑Stimulating Hormone (FSH), Luteinizing Hormone (LH), Diurnal 4x Cortisol

Restrictions:  US Only, Tests cannot be shipped to New York or Maryland. California residents require healthcare provider authorization. 

  • Will bill out-of-network insurance providers for some plans.

  • Payments accepted include VISA, Master Card, American Express, Discover Card, personal checks and US money order

  • FSA submission information available.

  • An abundance of educational information, FAQ listings, etc.

  • Email support

  • Phone suppor

PROS

Very comprehensive testing method with a lot of educational materials available, will bill some insurance companies and work with FSA payments

CONS

  • No online chat feature (that I could see) or app.

  • While the test is the most comprehensive of the three, it is quite costly.

BOTTOM LINE

The ZRT Fertility Profile Home Hormone Test Kit is an extremely comprehensive hormone panel, however is quite expensive when compared to other tests. It is perfect for women who want a full spectrum, comprehensive saliva and blood hormone panel to evaluate their fertility and hormone function. 


Article References:

Knudtson, J and McLaughlin, J. (n.d.) Menstrual Cycle. Retrieved from https://www.msdmanuals.com/en-gb/home/women-s-health-issues/biology-of-the-female-reproductive-system/menstrual-cycle

LetsGetChecked. Retrieved from https://www.letsgetchecked.com/us/en/female-hormone-test/

Nichols, H. (2018, January 2). "Everything you need to know about estrogen." Medical News Today. Retrieved from
https://www.medicalnewstoday.com/articles/277177.php

What are some possible causes of female infertility? (2017, January 31) Retrieved from https://www.nichd.nih.gov/health/topics/infertility/conditioninfo/causes/causes-female