What is Pharmazam™
Pharmazam is a physician ordered medication management system that integrates a smartphone app, a pharmacogenomics (PGx) DNA drug metabolism diagnostic test and analytical software to generate patient specific indications of Adverse Drug Reactions (ADRs) from Drug to Drug, Drug to Gene, Drug to Illness, Drug to Allergy, Drug to Food, and Drug to Lifestyle issues.
How Pharmazam Works
Pharmazam is a system of three integrated components consisting of a mobile device application (smartphone app), a pharmacogenomics (PGx) DNA drug metabolism diagnostic lab test and cloud computing interpretation software.
The Pharmazam App
The Pharmazam smartphone application is available free of charge from both Apple’s App Store and Google Play. The app works on all iOS and Android devices and takes takes up approximately 150 MB of memory storage on your phone.
The Pharmazam app acts primarily as the user interface between the system’s real-time interpretation engine to deliver results, enter information and receive push notifications from the system.
The app interface allows users to enter medication, drug lists, allergies, medical history and lifestyle factors into the system. Once analyzed, users can then send reports to physicians and family members for review. The check medication feature allows users to enter drug names, dosages or product NDC codes. A unique feature of the app is the “Scan Product Bar Code” feature that allows users to scan over-the-counter medication/nutritional product bar codes for analysis against previously entered drug or pgx test results.
This is a powerful tool that can operate as a free standalone app. That means the paid PGX or allergy tests are not a requirement. All of the medication management tools including Adverse Drug Reactions (ADRs), Drug to Illness, Drug to Allergy, Drug to Food, and Drug to Lifestyle issues will work upon setup without the genetic test. The genetic test can then be added at a later time.
The Pharmazam App Features Include:
- Works iOS and Android devices
- Simple Setup & Easy Controls
- Manage Your Whole Family’s Medications
- Organizes Your Medications in One Place
- Works With All Prescribed Medications
- Works With Most Over-the-Counter Drugs
- Manage Your Meds Easily Online
- Creates Concise Reports For Your Physician
- Automatically Updated Based on Scientific/Medical Research
If you don’t have a smartphone or mobile device, you can register for a web account from the company’s website online at app.pharmazam.com.
The Pharmazam Test
Pharmazam provides DNA health testing through it’s proprietary pharmacogenetics test (often abbreviate as PGx). Pharmacogenomics is the study of how medications react to a person’s specific genetic makeup. A PGx test is sometimes referred to as a DNA drug metabolism test of certain genes to determine how individuals are going to react to specific medications. The test results help to determine which medications will work, won’t work, and could possibly even kill you. It also helps to decrease the usual practice of “trial and error” dosing and can reduce the risk of Adverse Drug Reactions (ADRs).
PGx testing provides predictive information about a patient’s ability to metabolize certain medications and what effect that medication has on a patient, enabling optimal medication choice and dosing. This can provide a unique and personalized treatment strategy, shorten the time needed to find an effective medication, and reduce risk for adverse drug reactions. With a simple buccal swab test from the inside of your cheek, Pharmazam can reportedly determine your ability to metabolize certain drugs.
All Pharmazam testing is done by CLIA certified national laboratories that are fully accredited and licensed at the state and national level, which allows for the greatest accuracy within the parameters and limitations of current technology.
Pharmazam uses a third party FDA Cleared DNA collection kit from DNA Genotek. Current Pharmazam kits use their ORAcollect•DNA, a painless and easy-to-use DNA collection kit for self or assisted sample collection of buccal swab and/or saliva samples. The ORAcollect DNA
is intended for use in the non-invasive collection of human DNA from saliva, where the sample is isolated, stabilized, and suitable for use in Pharmazam’s PGx diagnostic test. Saliva samples collected using ORAcollect•Dx are stabilized and can be transported and/or stored long term at ambient conditions.
Pharmazam’s proprietary GSA V1 genotyping chip is run on Illumina’s next generation genetic sequencers to analyze 20,000 different genes and over 693,000 variants. By comparison, other popular DNA test on the market including 23andme only test around 23 genes and up to just 600 variants. Illumina, based in San Diego, California is a DNA industry leading provider of genetic sequencers, test chips, reagents, microarrays and related informatics. Illuminates primary industry competitor is Thermo Fisher Scientific, the Waltham, Massachusetts, multinational applied sciences company.
Expanding beyond DNA, Pharmazam has recently introduced an allergy test to it’s product offering. Medications may create a critical allergic response in patients however it’s not always the medication causing the reaction. An individual may be allergic to certain fillers or products that are used to manufacture or encapsulate medications providing a false negative reaction to the medication itself.
By combining the allergy test with it’s existing app, patients can avoid a potentially hazardous allergic reaction to a medication while providing alternate medication therapy suggestions. Once a patient’s Pharmazam A test results are loaded into the system, patients can check medications against their allergies prior to a medication being prescribed or even scan an over-the-counter bar code to determine incompatibility that could cause a potentially hazardous event.
Pharmazam Test Instructions.
Prior to taking the test, patients are asked to NOT eat, drink, smoke, chew tobacco, or use oral care products (such as mouthwash, toothpaste and whitening strips) 30 minutes before this test.
Step 1 is to rinse mouth with water right before test. Next, remove tube from pouch, then unscrew and reverse its’ cap. Do not spill contents of the tube + do not touch swab tip with fingers, teeth or any surfaces. Second, swab back and forth 20x inside each cheek (between gums & inner cheek). Next, unscrew the swab-cap and ensure contents are not spilled. Then seal the swab firmly inside of the tube and then shake it back and forth 10x. Finally, cap the vial tightly, and place it in the biobag. Next, seal the bag and completed form in the supplied box and return it via US prepaid mail. Download the Pharmazam app (or register online at Pharmazam.com) and then set up your profile.
The Pharmazam Software
The third and most important part of the Pharmazam System is it’s powerful drug to gene interpretation engine, a cloud-based pharmacogenetic interpretation software solution. At its core, the Pharmazam software analyzes some of the most advanced and comprehensive drug, genomic, and healthcare databases in the world to obtain information for medication management that is tailored specifically to your current health condition and genetic makeup. The software makes it easy to use providing almost instant results back through the app.
Consisting of complex algorithms and artificial intelligence, the Pharmazam software connects into some of the largest and most advanced healthcare databases in the world. Then by combining your DNA information and details from your profile, Pharmazam can quickly generate and provide detailed information to you and your doctor.
The result is a real-time P-Zam report on how that medication could affect you. Patients can then easily share reports with their physician prior to being prescribed a new medication. This allows doctors to make genetically based prescribing decisions.
Then Pharmazam automatically adds any prescribed medication or medication that could have a negative effect on your health to your health profile so that it can be used for all future medication requests. This feature will help patients avoid potentially fatal drug-to-drug interactions.
Pharmazam is designed to be completely secure, confidential and is completely HIPAA compliant. All data transmitted to and from Pharmazam partner labs and the Pharmazam software servers are encrypted using the most advanced security technology and HL7 protocols.
The Pharmazam Software provides cloud-based, real time analysis and reporting on the following:
- Drug to Drug Interaction
- Drug to Gene
- Drug to Allergy
- Drug to Disease Contraindication
- Drug to Food Interaction
- Drug to Lab Interference
- Known Lifesytle Issues
- Duplicate Therapy
- Min/Max Dosage guidance
- Patient Educational Materials
- Precautions (Geriatric, Pediatric, Pregnancy, Lactation)
- Prioritized Label Warnings
- Potential Side Effects
- Counseling Messages
- Dosage Range Check
The Pharmazam Team
Pharmazam also maintains a robust group of medical directors, licensed medical experts, and highly trained healthcare experts on staff as well as an advisory board consisting of leading industry experts.
Do I Need A Doctor to Get The Pharmazam Test?
A doctor interaction is required. Test kits can either be ordered by your physician or by a Pharmazam physician. Patients can request a test kit directly online, then the Pharmazam medical team will review the request and ordered a lab test kit to be shipped to patients. Completed test results can be viewed and patient specific medications and drug Interactions review from the Pharmazam App.
Physicians can also register with Pharmazam for PGx testing of their patients. Interested Doctors simply complete the online Pharmazam Physician Test Request form. Once approved, kits will then be shipped to the physicians’ office, whereby patients can then come in to provide a DNA sample and the physician’s office will ship DNA specimen back to the Pharmazam lab.
When the test is complete and released by the Pharmazam medical department, the results will automatically be connected to both the patients app and physicians portal for immediate use.
Is there a cost for Pharmazam?
The app is free of charge. You can download the App or register online at Pharmazam.com for no initial fee and have the option to upgrade the app’s features for a small fee. If you choose to add the PGx test there is a one-time investment of $399.00.
Does insurance cover the cost of the Pharmazam Test?
Pharmazam is CASH pay (or self-pay) only. They do not accept any form of insurance however some insurance companies might apply the cost to your deductible or reimburse you for the cost of the test.
If ordered by your physician, the Pharmazam test would be considered a qualifying medical expense eligible for reimbursement or payment by some healthcare savings accounts (HSA’s).
Who Benefits From Pharmazam
With 82% of Americans taking at least one medication and 29% of Americans taking 5 or more medications, it’s no wonder that the 4th leading cause of death in the U.S. are Adverse Drug Reactions. Enter Pharmazam, a powerful medication management tool designed to benefit just about everyone, from newborns to the elderly.
The Pharmazam PGx test combined with it’s interpretive results can help tell from birth what medications should or should not be taken, what dosages are right, and what medications could possibly even kill you and the test results never change over the course of your life. Because your DNA doesn’t change over time, the test works equally well on infants and senior citizens.
More and more patients are being categorized as polypharma patients . Polypharmacy is known as the simultaneous use of multiple drugs by a single patient, for one or more conditions.
Being a caregiver to a polypharma loved one can become extremely burdensome especially when it comes to managing their medications.
As a greater number of medications are used this becomes more complicated. Non-prescription, over-the-counter medications, supplements, vitamins, minerals, and prescribed medications must all be considered.
Titrating the correct meds and dosages is difficult for the elderly. Pharmazam considers all types of prescription and over-the-counter medications and can assist in advice on the optimal mix or prescription dosages.
One last benefit of Pharmazam is in it’s ability to help reduce medical errors. The Pharmazam app protects patients by minimizing errors with pharmaceutical bar code scanning. A simple check of the bar code against the drug purchase can confirm compatibility with the patients existing test results and entered drug list.
Prior to taking a new medication you simply scan the product barcode or enter the name into the app or on the website and it instantly analyzes it by accessing multiple leading healthcare databases and then compares the results to your specific health profile.
In addition to the above described patient benefits, the Pharmazam system is being adopted by a wide variety of industries for its’ ability to save lives, prevent accidents, enhance pharmaceutical care, and reduce medical expenses.
Clinicians, employers, hospitals, insurers and pharmacies alike are beginning to enthusiastically embraced PGx testing for it’s ability to mitigate risk and reduce liability from prescribed medications, it’s ability to match care decisions to patient specific DNA, and provide a monitoring mechanism of patient medications.
Pharmazam Helps Reduce Clinical Liability
If the patient takes the medication and has an adverse reaction, the physician can be held responsible for malpractice. With the rising cost of medical malpractice insurance, clinicians, healthcare facilities and pharmacists are increasingly turning to pharmacogentic solutions like Pharmazam to minimize adverse drug reactions.
Because every patient metabolizes drugs differently, PGx test results identify patient’s individual genetic makeup and responses to various medications. Incumbent on the Hippocratic Oath is a doctors goal of not causing harm. PGx tests like Pharmazam provide clinicians with an efficacious way of reducing risk of injury or death from prescribed medications by improving a doctors ability to make patient specific medical decisions.